Posted by Miguel (209.42.192.28) on July 27, 2000 at 18:49:45:
In Reply to: Yeah - I see what you're saying, to answer that we must first establish the following... posted by Flash on July 27, 2000 at 05:47:30:
K, I am right now at the tip of very skinny, long,
bouncing branch of pseudo-science...perhaps more
in the sci-fi sector than anything with this thought;
I learned from one abstract that platelets have
5-HT2A receptors. Now, why in the hell do platelets
have that receptor? Why is it needed that 5-HT binds
there? ....Here I go again.....how about this:
Serotonin is secreted according to a
second messenger (i.e.: left anterior descending
coronary calling all points...left anterior descending
coronary calling all points...Brain comes in -
We copy LAD. LAD - thank you brain...need your help
bud, copy.....Brain What can we do for you now
LAD, copy.....Well brain - says the LAD - this dude
stopped jogging an hour ago so ...heck! I am tired
of being all dilated and carrying all this RBCS full of
O2 around...this guy's septum and left ventricle
don't need that much O2 any more...unfortunately,
he is had a few too many burgers from heaven and the
endothelium is covered with plaque...errr...no EDRF nor
EDCF is being released to autoregulate, copy? Brain-
yes, I copy...so what can I do for you? copy...
LAD - well bud...can you send some serotonin down
to help me autoregulate a bit? copy...Brain, ERRR...
that is an afirmative, copy? LAD - thanx bud, over and out...
Brain - OK pitutitary start pumping some sero for
a bud in need, copy. Pituitary - Err...that is an
affirmative brain, copy, over and out.
Brain - K...APB to all available platelets...
Platelets here, we are ready...over and out...
and the platelets take up the serotonin. The region in
need sends a second messenger to let the platelets
know where to go and dump their precious load and presto.
Miguel